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What can I take over the counter for anxiety? Do Over-the-Counter Medications Work for Anxiety? antihistamines like diphenhydramine (Benadryl) herbal remedies (e.g., Kava Kava, l-theanine, 5-hydroxy-tryptophan or 5-HTP) passionflower, valerian, lavender, lemon balm, skullcap, chamomile. muscle relaxants, sleep medications. cough syrups, cold medicines, painkillers.
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