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I am so thankful for Gleevec! I did have some side-effects but prior to Gleevec, taking interferon and hydroxyurea led to much more severe side effects. I had aching limbs, and I now have a skin reddening/rash--like rosacea on my cheeks and my upper arms are reddish--like a mild sunburn. I have tummy issues now--gurgling, diarrhea, cramping, etc., but they are easily managed with imodium. Gleevec has extended my survival and I had the honor of meeting Dr Druker who developed the drug, at Oregon Health and Science University. He was absolutely wonderful as was the care I received there.



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Gleevec is a really wonderful medication that saves lives and helps people maintain clear mind. I'v been on it for more than seven years now and I've had no side effects with it. You just have to be careful when taking the medication together with other strong drugs. For example I had to stop taking Interferon in order to get my heart function back to normal. But that's not a problem anymore as Gleevec offers so many more benefits. First of all I am still alive due to this medication. And I have been in remission for seven years, isn't it an evidence of the highest quality of the drug! I know that many people complain of nasty side effects and it's natural as we are all individuals and there can be no single solution equally good for all of us. So for some people Gleevec is the best solution, others have to continue their search. But when it comes to cancer, the most important thing is not to hang your head and continue searching. Cause there is a solution, you just have to find it. God bless us all!

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CT guided biopsy were done, and cultures from both subsequently grew Rhodococcus equi.

Imatinib mesylate-induced interstitial pneumonitis.

Cases of fatal liver failure and severe liver injury requiring liver transplants have been reported with both short-term and long-term use of GLEEVEC.

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Complete cytogenetic response is not obtained in 6-12 months of therapy.

Do not take 2 doses of IMBRUVICA on the same day to make up for a missed dose.

Should adolescents with acute lymphoblastic leukemia be treated as old children or young adults?

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Follow-up is performed at close intervals, possibly with 18fluoro-deoxyglucose-positron emission tomography ( 18FDG-PET), to assess response to therapy.

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Alternative treatments are therefore needed to improve the prognosis of neuroblastoma patients with high-risk disease.

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Either problem, however, may lead to the need for total hip arthroplasty.

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There is also controversy about whether the prognostic significance of CRLF2 abnormalities should be analyzed based on CRLF2 overexpression or on the presence of CRLF2 genomic alterations.

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The current study population included 5 patients with HES and 2 patients with eosinophilia-associated CMD (eos-CMD) who were treated with imatinib and prospectively followed for response and toxicity assessments.

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This remission and relapse are likely what occurred in our patient as studies have that shown sarcoid and other autoimmune diseases can actually be exacerbated during interferon therapy.

This case underscores the importance of early diagnosis of highly communicable diseases in populations with low levels of immunity.

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Favorable long-term follow-up results over 6 years for response, survival, and safety with imatinib mesylate therapy in chronic-phase chronic myeloid leukemia after failure of interferon-alpha treatment.

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Combining imatinib with inhibitors of other key cellular enzymes, such as the farnesyltransferases, is another rational strategy.

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