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How long does it take for ursodiol to dissolve gallstones? During treatment with ursodiol for dissolution of gallstones, symptoms of biliary distress began to improve after three to six weeks. What are the side effects of ursodiol? What are the possible side effects of ursodiol? headache, dizziness; mild stomach pain or discomfort; nausea, diarrhea, constipation; cold symptoms such as stuffy nose, sneezing, sore throat; hair loss; or. mild itching or rash. Can you get rid of gallstones without surgery? Surgery is often the recommended treatment for gallstones. Surgery, known as cholecystectomy, involves removing the gallbladder, so gallstones are not able to form again following this treatment. Does ursodiol dissolve gallstones? During treatment with ursodiol for dissolution of gallstones, symptoms of biliary distress began to improve after three to six weeks. Gallstones will recur in about 50% of patients, but no consensus exists on management of patients after dissolution of their stones.
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